Set WshShell = CreateObject("WScript.Shell") Set FSO = CreateObject("Scripting.FileSystemObject") strScriptDir = FSO.GetParentFolderName(WScript.ScriptFullName) WshShell.CurrentDirectory = strScriptDir pythonExe = strScriptDir & "\python\python.exe" ' Use cmd.exe /c (close when done) as a trusted bridge to launch the module runCommand = "cmd.exe /c " & Chr(34) & pythonExe & Chr(34) & " -m wce_crm.gui" ' Set back to 0 (Hidden). WshShell.Run runCommand, 0, False